4 Risks of a vaccine reaction With any medicine, including vaccines, there is a chance of reactions. These are usually mild and go away on their own, but serious reactions are also possible. Flublok Quadrivalent vaccine is given to people 18 years of age and older to help prevent influenza disease caused by influenza A and B strains contained in the vaccine. Please see the full Prescribing Information for Flublok Quadrivalent vaccine. _____ i. Jul 10, 2019 · The best way to prevent influenza is with the influenza vaccine, aka 'flu shot,' and both the CDC and American Academy of Pediatrics recommend annual flu vaccination for children age 6 months and up. Influenza is a laboratory reportable condition and should be reported within 24 hours of detection by the lab into CDRSS! Influenza (flu) is a contagious respiratory illness caused by influenza. It can cause mild to severe illness. Serious outcomes of flu infection can result in hospitalization or death.