Compare Enfamil vs. Enfamil Premium Newborn, which is better for uses like: Reflux, Colic and GERD. Compare head-to-head ratings, side effects, warnings, dosages, interactions and patient reviews. Enfamil vs. Similac. Diffen › Parenting › Baby. When choosing infant formula, parents usually decide based on the nutrition, safety record, range of products, availability and prices. This is an unbiased comparison of Similac and Enfamil, the two largest baby formula manufacturers, on these parameters. Enfamil NeuroPro Infant is a 20 Cal/fl oz milk-based, iron-fortified, routine formula for full-term infants 0–12 months. Enfamil NeuroPro Infant has a fat-protein blend of MFGM and DHA previously found only in breast milk * . Enfamil formula is made using palm olein oil; Similac does not. One study suggests that formulas with a fat blend including palm olein oil (e.g., Enfamil, Prosobee) cause less frequent and firmer stools. Similac claim that their infant formula provides 50% more calcium absorption than Enfamil. Jul 05, 2019 · Similac Sensitive is different from Enfamil Gentlease in that it is lactose-free. Enfamil Gentlease, on the other hand, utilizes gentle proteins. The package lists partially hydrolyzed nonfat milk and whey protein concentrate solids as ingredients in the formula. Similac Sensitive lists milk protein isolate as a source of protein.