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Spit Up versus Acid Reflux Baby spit up and acid reflux (gastroesophageal reflux) are actually the same thing. It looks like you have javascript turned off. This What is the Difference Between Baby Spit Up and Acid Reflux? page on EmpowHER Women's Health works best with javascript enabled in your browser. Spitting up can sometimes become more than a laundry problem and reflects a medical problem, such as a formula allergy , pyloric stenosis, or gastroesophageal reflux. SPIT UP TIP Try what we call the fist test: Tiny babies have tiny tummies, about the size of their fists. From birth my baby started on Similac Pro-Advanced and she was constantly spitting it up. She was switched to Similac for Spit-up while we were still in the hospital. After a few feedings she had stopped spitting up. I'm extremely thankful for this formula! Thank you!! Feb 19, 2016 · If your baby spits up, or has problems with your formula?? Watch this!! If your baby spits up, or has problems with your formula?? ... Best New Mom Tips: Swaddle a Baby, Change a Diaper, and More! ... Aug 26, 2011 · Few weeks later mixed 1 part milk to 7 parts formula, the still spit up, I backed off again. Few weeks later I tried one more time before deciding to have them allergy tested or trying soy, and it worked, but still very gradually. My 3rd has never had formula, but she went straight to whole milk once she turned one, no issues whatsoever.