Of tuberculosis vaccine


The only existing vaccine against tuberculosis (TB), Bacille Calmette-Guérin (BCG), created in 1921, has variable protective efficacy. WHO recommends vaccinating HIV-uninfected infants with BCG as it provides protection against severe extrapulmonary (non-lung) forms of paediatric TB. INTRODUCTION. Tuberculosis (TB) is a disease rich in paradoxes. It was one of the first diseases for which the causative agent (Mycobacterium tuberculosis) was identified, and one of the first for which a vaccine was developed (20, 80). To date, the Mycobacterium bovis bacillus Calmette-Guérin (BCG) vaccine remains the only licensed vaccine for the prevention of TB. It is traditionally given to newborns, and in that population, it has a protective effect. Researchers develop and test a potential new tuberculosis vaccine in mice. Tuberculosis is an infectious disease caused by the bacterium, Mycobacterium tuberculosis (Mtb). Tuberculosis is a large threat because it is able to live in a host without obvious symptoms for a period of time before ...